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Rosai-Dorfman disease with cutaneous manifestation (sinus histiocytosis with massive lymphadenopathy)


European Journal of Dermatology. Volume 16, Number 3, 293-6, May-June 2006, Clinical report

Free Article  

Author(s) : Brigitte Coras, Susanne Michel, Michael Landthaler, Ulrich Hohenleutner

Summary : We report a 73-year-old woman with the typical findings of “Rosai-Dorfman disease” (RDD) including massive, painless lymphadenopathy, fever and multiple, asymptomatic cutaneous lesions on her face, collum and neck. Histologically, the lesions were marked by characteristic large macrophages exhibiting emperipolesis.

Keywords : sinus histiocytosis, Rosai-Dorfman disease, lymphadenopathy, cutaneous manifestation, emperipolesis

 

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