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The combined occurrence of macular amyloidosis and prurigo nodularis


European Journal of Dermatology. Volume 10, Number 4, 297-9, June 2000, Cas cliniques

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Author(s) : Can BAYKAL, Esen OZKAYA-BAYAZIT, Gonca GOKDEMIR, Reyhan DIZ KUCUKKAYA

Summary : The association of prurigo nodularis (PN) and macular amyloidosis (MA) has not been reported before. Although pruritus related frictional trauma is a well-known cause of PN, its role in the development of MA has always been questioned. We herein report two cases with chronic liver disease and iron deficiency who concomitantly developed MA and PN lesions. Pruritus was the preceding factor and both lesions were confined to scratched areas. The association of two otherwise uncommon dermatoses in pruritic patients and their characteristic distribution might indicate an important role for pruritus-induced scratching in the pathogenesis of MA, too.

Keywords : cutaneous amyloidosis, macular amyloidosis, prurigo nodularis, pruritus, scratching.

 

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