Author(s) : H. Tomková, M. Ueda, K. Arakawa, J. Arata, Department of Dermatology, Okayama University Medical School,
2-5-1 Shikata-cho, 700 Okayama City, Japan..
Summary : We report a case of cheilitis granulomatosa of the upper lip associated with focal, odontogenic infection, nickel and cobalt hypersensitivity, and IgD lambda
monoclonal protein in a 58-year-old woman. The lip swelling resolved almost completely within about six months under treatment with indomethacin, 100 mg a day. Further examination revealed that she had asymptomatic IgD myeloma.
Figure 1. Persistent, non-tender swelling of the upper lip. (A)
frontal view, (B) lateral view.
Figure 2. Photomicrograph of a biopsy of the upper lip. High-power magnification
of perivascular, lymphoid-plasma-cellular infiltrate (hematoxylin-eosin,
x 110).
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