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 Printable version |
Drug-induced urticaria |
European Journal of Dermatology. Volume 11, Number 3, 181-7, May - June 2001, Article revue
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 Free Article
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Author(s) : F. Cousin, K. Philips, B. Favier, J. Bienvenu, J.F. Nicolas |
Summary : The occurrence of acute urticaria during treatment with drugs is a frequent event which poses two problems: 1) is the urticaria connected with the drug administration or with the underlying pathology which led to the prescription of the drug; 2) is the urticaria allergic in origin, i.e. due to specific immunity triggers, in particular IgE directed against the drug, or is the urticaria pseudo-allergic in origin, i.e. due to non-specific activation of mastocytes [1]? This question is of major importance because allergic events caused by IgE are potentially fatal while pseudo-allergic events are only rarely life-threatening. In this article we will not deal with contact urticaria where the cause is easily identifiable [2]. |
Keywords : urticaria, anyphylaxis, drug intolerance, IgE, pseudo-allergy. |
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