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 Printable version |
Generalized eruptive histiocytoma of childhood associated with rheumatic fever |
European Journal of Dermatology. Volume 9, Number 7, 548-50, October - November 1999, Cas cliniques
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 Free Article
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Author(s) : Y. Matsushima, K. Ohnishi, O. Ishikawa |
Summary : We describe a widespread papular eruption in a 5-year-old girl with rheumatic fever. Histological examination revealed a dense histiocytic infiltration in the dermis. On immunohistochemical studies, the cells were positive for vimentin, CD68, MAC387, alpha1-antichymotrypsin and lysozyme, but negative for CD1a and S-100 protein. Electron microscopic studies showed no Birbeck granules in their cytoplasm. A diagnosis of generalized eruptive histiocytoma of childhood was established. The skin lesions completely disappeared within 8 months. |
Keywords : electronmicroscopy, generalized eruptive histiocytoma, pediatric case, rheumatic fever. |
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