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 Printable version |
HPV 29-associated spotted hyperpigmentation of the face |
European Journal of Dermatology. Volume 12, Number 2, 189-90, March - April 2002, Cas cliniques
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 Free Article
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Author(s) : Susanne JACOBS, Jens Malte BARON, Albert RUBBEN, Elke-Ingrid GRUSSENDORF-CONEN |
Summary : A healthy immunocompetent 40-year-old man presented with spotted hyperpigmentation of the face. Skin-biopsies taken from these lesions revealed slight acanthosis of the epidermis with vacuolization within the keratinocytes in the upper malpighian layer similar to HPV-induced cytopathic viral effects. Polymerase chain reaction analysis and subsequent direct DNA sequencing could clearly demonstrate the presence of HPV 29 DNA in the hyperpigmented macules. To our knowledge, this is the first report of facial hyperpigmented lesions induced by HPV 29. |
Keywords : hyperpigmentation, humanpapillomavirus type 29, polymerase chain reaction. |
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