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 Printable version |
Pruritic eosinophilic papular eruption revealing HIV infection |
European Journal of Dermatology. Volume 12, Number 6, 600-2, November - December 2002, Cas cliniques
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 Free Article
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Author(s) : Patrizia TEOFOLI, Claudio BARBIERI, Sabatino PALLOTTA, G. FERRANTI, Pietro PUDDU |
Summary : Eosinophilic folliculitis (EF) is a rare follicular pruritic papular eruption observed in association with human immunodeficiency virus (HIV). The diagnosis of eosinophilic folliculitis is based on the histologic findings consisting of a sterile inflammatory infiltrate rich in eosinophils involving hair follicles. EF in HIV patients is believed to be an immunoinflammatory response directed either at follicular or skin flora antigens in the late-stage of HIV infection. In this stage, immune response is characterized by a shift from a Th1- to a Th2-dominant cytokine profile and an increased secretion of interleukin-4 and interleukin-5, both known to promote eosinophilia. We describe a case of HIV-associated eosinophilic folliculitis in a 30-year-old black woman referred to us for a pruritic follicular eruption without any other clinical symptom related to the acquired immunodeficiency syndrome. HIV infection presenting with EF has been rarely reported and its occurrence in women is also very rare. |
Keywords : eosinophilic folliculitis, pruritic papular eruption, HIV infection, Th2-immune response. |
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