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Prominent transepithelial elimination of collagen in keratoacanthoma


European Journal of Dermatology. Volume 7, Number 3, 188-9, April - May 1997, Cas cliniques


Author(s) : A.R. MacKenzie-Wood, S. Kossard

Summary : Transepithelial elimination of collagen fibres occurs in perforating verruciform collagenoma (PVC) and reactive perforating collagenosis (RPC). Both are rare conditions in which traumatically altered collagen is eliminated through the epidermis. We report an example of a keratoacanthoma (KA) demonstrating prominent transepithelial elimination of collagen and discuss this phenomenon and its relationship to the perforating collagenoses. A review of 120 KAs showed that this phenomenon can be observed in 4% of cases.

Keywords : keratoacanthoma, perforating verruciform collagenoma, reactive perforating collagenosis, transepithelial elimination.

 

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