|
|
 |
 |
| |
 Printable version |
PAIR-gynaecology: multi/interdisciplinary for gynecologic cancer research. Problems needed to be resolved |
Bulletin du Cancer. Volume 99, Number 4, 479-98, Avril 2012, Synthèse
|
 Résumé
Texte intégral
|
Author(s) : Isabelle Ray-Coquard, Franck Chauvin, Éric Leblanc, Christophe Caux, Hélène Hoarau, Franck Bonnetain, Véronique Christophe, Xavier Sastre-Garau, Gwendal Lazennec, Laurent Poulain, Christine Haie-Meder, Éric Pujade-Lauraine, Michel Salzet, Éric Deutsch, Mojgan Devouassoux, Frédérique Penault Llorca, Fabrice Lecuru, Sophie Taieb, Patrick Arveux, Charles Theillet, Florence Joly |
Summary : Each year, 13,000 newly gynecologic cancers are diagnosed in France. Gynecologic cancers were specifically heterogeneous (localisations, histologic subgroups, age class, etc). This work was delineated for a national call dedicated to gynecologic cancers. This review reports the major needs in terms of scientific research dedicated to gynecologic cancers in the biologic, epidemiology, human and sociologic fields. For example, medico-economic strategies adapted to ethnosociologic context, specifically for cervix cancer, took important part of the epidemiologic research. Impact of gynecologic cancer in terms of symptoms and late effects, quality of life after treatments and fertility needs to be specifically explored. For fundamental research, molecular characterisation, biologic markers, impact of immunology and genetics represent the major part of the field need to be explored. Finally, therapeutic and diagnosis innovations, optimization of treatments strategies and development of predictive models in order to perform individual prediction taking into account several risk factors (clinical and molecular) to offer help in management of gynecologic cancers are required. |
Keywords : gynecologic cancers, epidemiology, molecular biology, genetics, imagery, innovations, social science |
|
