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 Printable version |
Renal involvement in cancer and renal paraneoplastic syndromes |
Bulletin du Cancer. Volume 99, Number 3, 263-75, Mars 2012, Synthèse
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 Résumé
Article gratuit
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Author(s) : Juliette Thariat, Benoit Vendrely, Sophie Roca, Alain Ravaud, Jacques-Olivier Bay, Alexis Lacout, Pierre-Yves Marcy, Antoine Thyss, Jean-François Besancenot |
Summary : <\;p>Renal alterations in the context of neoplastic disease are relatively frequent manifestations but are overall poorly reported.<\;/p><\;p>A search in the English and French literature was performed using the following key words: “cancer”, “renal”, “paraneoplastic syndrome”, “glomerulopathy” and “kidney failure”.<\;/p><\;p>The various renal manifestations can be divided into specific and paraneoplastic. They include paraneoplastic glomerulopathies (membranous glomerulonephristis being the most frequent), direct involvement of the renal parenchyma, hydroelectrolytic abnormalities (hypercalcemia, inappropriate antidiuretic hormone secretion…), retroperitoneal fibrosis, micro-angiothrombotic disease and tumor lysis syndrome. Anticancer and symptomatic treatments do not guaranty complete recovery in all cases.<\;/p><\;p>The frequency and the severity of some renal manifestations associated with malignant hemopathies and carcinomas indicates a need for initial renal-oriented work-up and follow-up.<\;/p> |
Keywords : cancer, renal, paraneoplastic syndrome, glomerulopathy, kidney failure |
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