Hysteroscopic injection in sentinel node biopsy for endometrial cancer increase the frequency of para-aortic drainage : place of the para-aortic lymphadenectomy ?

Denys Clément; Olivier Morel; Cécile Malartic; Grégory Akerman; Emmanuel Barranger

doi:10.1684/bdc.2007.0237



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Hysteroscopic injection in sentinel node biopsy for endometrial cancer increase the frequency of para-aortic drainage : place of the para-aortic lymphadenectomy ?
Bulletin du Cancer. Volume 94, Number 7, 675-9, Juillet-Août 2007, Synthèse
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Author(s) : Denys Clément, Olivier Morel, Cécile Malartic, Grégory Akerman, Emmanuel Barranger
Summary : In cancer research, regional lymph node status is a major prognostic factor and a decision criterion for adjuvant therapy. The sentinel node procedure, which has emerged to reduce morbidity of extensive lymphadenectomy, remains a major step in the surgical management of various cancers. In endometrial cancer, the sentinel node biopsy is still at the stage of feasibility. The main problem of the diffusion of the sentinel node biopsy in endometrial cancer is the absence of injection site consensus. The different injection sites (myometrial, pericervical and hysteroscopy) allow to identify para-aortic lymph node drainage. In this article, we review the interest of hysteroscopic injection in endometrial cancer. This injection site could contribute to select the patients potentially being able to profit from a lombo-aortic lymphadenectomy.
Keywords : sentinel lymph node, endometrial cancer, hysteroscopic injection, patent blue, radio-isotope, para-aortic drainage