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Clinical Practice Guidelines 2004. Standards, Options and Recommendations for the management of patient with adenocarcinoma of the stomach: radiotherapy (therapeutic evaluation)


Bulletin du Cancer. Volume 92, Number 4, 381-409, Avril 2005, SOR

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Author(s) : Marc Ychou, Guillaume Gory-Delabaere, Pierre Blanc, Lise Bosquet, Jacqueline Duffour, Marc Giovannini, François Guillemin, Claire Lemanski, Frédéric Marchal, Bruno Masson, Yacine Merrouche, Geneviève Monges, Antoine Adenis, Jean-François Bosset, Olivier Bouché, Thierry Conroy, Denis Pezet, Jean-Pierre Triboulet

Summary : Context: The « Standards, Options and Recommendations » (SOR) project, started in 1993, is a collaboration between the Federation of French Cancer Centers (FNCLCC), the 20 French regional cancer centers, and specialists from French Public Universities, General Hospitals and Private Clinics. The main objective is the development of clinical practice guidelines to improve the quality of health care and the outcome of cancer patients. Objectives: To elaborate clinical practice guidelines for patients with stomach adenocarcinoma. These recommendations cover the diagnosis, treatment and follow-up of these tumors. Methods: The methodology is based on a literature review and critical appraisal by a multidisciplinary group of experts, with feedback from specialists in cancer care delivery. The Standards, Options and Recommendations are thus based on the best available evidence and expert agreement. Results: This guidelines presents the synthesis of the data concerning the evaluation of the therapeutic ones. The main questions concern the type of gastrectomy to realize (Total Gastrectomy or gastrectomy subtotale), the extent of the lymphadenectomy (D2, D3 versus D1, D3, D2 versus D4) and the role of postoperative chemotherapy and adjuvant concomitant chemoradiotherapy.

Keywords : adenocarcinoma, stomach neoplasms, surgery, chemotherapy, therapeutics, radiotherapy, combined modality therapy, research evaluation, meta-analysis, survival rate, practice guideline

 

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