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Atypical mesoblastic nephromas with metastases at diagnosis?


Bulletin du Cancer. Volume 84, Number 8, 807-12, Août 1997, Articles originaux

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Author(s) : Khalouk Fallouh, Arnauld Delarue, Philippe Petit, Marie-Anne Chrestian, Michèle Portas, Nicole Horschowski, Jean-Louis Bernard

Summary : The diagnosis of a metastatic kidney tumor arising in a 2-month infant is discussed between atypical mesoblastic nephroma and clear cell sarcoma. The precocity of distant metastases, their location in bone marrow, liver and thoracic soft tissues, and their association with myelofibrosis set up an original clinical presentation which seems to have never been described elsewhere. Treatment strategy with surgery of the primary followed by a polychemotherapy combining vincristin-etoposide-ifosfamide and the short term follow-up are reported.

Keywords : mesoblastic nephroma, clear-cell sarcoma, kidney tumor, infant.

 

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