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 Printable version |
Usefulness of a pharmacokinetic approach for clinical antineoplastic chemotherapy evaluation |
Bulletin du Cancer. Volume 86, Number 4, 341-4, Avril 1999, Méthodologie
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 Résumé
Article gratuit
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Author(s) : François Lokiec |
Summary : Pharmacokinetics, which is the study of the drug becoming in the body, is an important approach of new drug evaluation. Anticancer drugs have mostly a very narrow therapeutic index which leads to a delicate clinical use. Pharmacokinetics permits the prediction of the occurrence of iatrogenic toxicities taking into account the interpatient variability of the pharmacokinetic parameters. |
Keywords : pharmacokinetics, anticancer drugs, pharmacokinetic parameters. |
