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 Printable version |
Weekly administration of paclitaxel in the treatment of metastatic breast cancer: from rational to practice |
Bulletin du Cancer. Volume 89, Number 3, 275-82, Mars 2002, Synthèses
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 Résumé
Article gratuit
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Author(s) : Mario Campone, Pierre Fumoleau |
Summary : Clinical studies showed that paclitaxel is active as single agent and in combination chemotherapy for the management of metastatic breast cancer. A variety of doses and administration schedules have been evaluated in phase II and III trials. Weekly administration of paclitaxel which is generally well tolerated increases the therapeutic index (efficacy/safety) resulting from anti-angiogenic and pro-apoptotic effects. |
Keywords : paclitaxel, breast cancer, weekly administration, trastuzumab. |
