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Local control in the management of cancer: a few thoughts


Bulletin du Cancer. Volume 88, Number 7, 693-9, Juillet 2001, Articles originaux

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Author(s) : Jean-Pierre Gérard, Olivier Chapet, Michel Cucherat, Pascale Romestaing, Françoise Mornex, Jean-Yves Bobin, Pascal Roy, Véronique Favrel

Summary : Cancer is still considered from a physiopathological point of view as a disease of the cell. This concept is underlying the idea of cure. Treatment with curative intent should aim at eradicating all the tumoral cells. Local control is mandatory and essential in cancers localized in organ with vital function. In breast cancer a complex and controversial relationship exists between local relapse and increased risk of fatal distant metastasis. In case of organ preserving treatment, a complete local control is necessary from the start. If a too high risk of local relapse is foreseable, conservative treatment should not be recommended.

Keywords : local tumor control, metastasis, cancer survival, conservative treatment.

 

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