Médecine et chirurgie du pied


Buerger’s disease Volume 23, issue 2, Août 2007


Présenté au congrès de la SFMCP/SFMA à Paris, les 1er et 2 décembre 2006

Buerger’s disease, also called thromboangiitis obliterans (TAO), is a non-atheromatous disease of the arteries and a specific and unique entity. This disorder consists of a segmentary thromboangiitis affecting medium-and small-calibre arteries as well as veins of the ends of the upper and lower extremities. It is found in young male adults and smokers, and unfolds as a series of attacks. Diagnosis is difficult to confirm without specific markers. In terms of therapy, the complete cessation of smoking is the corner-stone of all treatment measures, which include local care. Surgery is a solution of last resort. Although the pathophysiology of this disorder is not fully understood, future research will focus on discovering powerful vasodilators and factors that stimulate angiogenesis.