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Journal de Pharmacie Clinique

Naloxone per os in the treatment of opioid-induced constipation: case report of a patient resistant to conventional therapeutic Volume 21, issue 2, Juin 2002


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Service de soins de suite et unité de long séjour, Centre hospitalier de Loos, 22, rue Henri-Barbusse, 59120 Loos, France.
  • Key words: opioid-induced constipation, specific antagonist of morphine, palliative care.
  • Page(s) : 109-14
  • Published in: 2002

The opioid-induced constipation in palliative care is an important worry for the patient, nurses and physicians. The usual laxative's treatments can be powerless to relieve a patient. The help of specific antagonist of morphine (naloxone) might to improve the situation considerably. Through a clinical observation and review of literature, this paper deals with the way of using naloxone per os.