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Epileptic Disorders

The Educational Journal of the International League Against Epilepsy

Transient periodic lateralised epileptiform discharges (PLEDs) following internal carotid artery stenting Volume 14, issue 1, March 2012

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Authors
Department of Neurological, Behavioural and Neurosurgical Sciences, Section of Neurological Sciences, Department of Neuroscience, Section of Neurology, Department of Neuroimaging and Neurointervention, University of Siena, Italy
  • Key words: PLEDs, carotid artery stenting, EEG periodic discharges
  • DOI : 10.1684/epd.2012.0487
  • Page(s) : 85-9
  • Published in: 2012

Background. Periodic lateralised epileptiform discharges (PLEDs) are EEG patterns consisting of periodic or pseudoperiodic unilateral, focal or hemispheric epileptiform discharges at a rate of 1-2 Hz. PLEDs may be triggered by acute brain injuries or systemic metabolic changes such as fever, hyperglycaemia or electrolyte imbalance and may result in disturbance of consciousness and/or neurological deficits. Case report. A 58-year-old female with a history of focal epilepsy and deep brain haematoma presented with acute change in awareness, associated with EEG evidence of PLEDs, three days after a left internal carotid artery stenting procedure. Clinical examination, laboratory testing and MRI were unchanged with respect to pre-stenting investigations. Conclusion. In this patient, PLEDs may have been triggered by local haemodynamic changes due to reperfusion after stenting in a previously damaged brain area.