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Epileptic Disorders

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The ventral precuneal-posterior cingulate region as a site of epileptogenicity Volume 24, issue 5, October 2022

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Authors
1 School of Medicine, Central Michigan University, Mount Pleasant MI, USA
2 Department of Clinical Neurosciences, Spectrum Health, Grand Rapids, MI, USA
3 College of Human Medicine, Michigan State University, Grand Rapids, MI, USA
4 Imaging Physics, Department of Radiology, Spectrum Health, Grand Rapids, MI, USA
Correspondence:
Lee Elisevich
School of Medicine, Central Michigan University, Mount Pleasant MI, USA

The ventral precuneal and posterior cingulate area (VP-PC) represents a distinct but topographically variable mesial parietal site of epileptogenicity that may manifest as a common temporal lobe-mediated ictal expression. In a review of records of 62 presumptive epilepsy surgery cases, two cases of primary epileptogenicity expressed within the VP-PC were identified and are detailed to bring attention to this electroencephalographically-hidden area of ictal expression. Details of their investigation and surgical treatment illustrate distinctly different approaches addressing the problem and bringing about a seizure-free outcome.