Epileptic Disorders
MENUThe ventral precuneal-posterior cingulate region as a site of epileptogenicity Volume 24, issue 5, October 2022
Authors
1 School of Medicine, Central Michigan University, Mount Pleasant MI, USA
2 Department of Clinical Neurosciences, Spectrum Health, Grand Rapids, MI, USA
3 College of Human Medicine, Michigan State University, Grand Rapids, MI, USA
4 Imaging Physics, Department of Radiology, Spectrum Health, Grand Rapids, MI, USA
Correspondence:
Lee Elisevich
School of Medicine, Central Michigan University, Mount Pleasant MI, USA
- Key words: precuneus, posterior cingulate, default mode network, temporal lobe epilepsy, responsive neurostimulation, laser interstitial thermal therapy
- DOI : 10.1684/epd.2022.1457
- Page(s) : 934-40
- Published in: 2022
The ventral precuneal and posterior cingulate area (VP-PC) represents a distinct but topographically variable mesial parietal site of epileptogenicity that may manifest as a common temporal lobe-mediated ictal expression. In a review of records of 62 presumptive epilepsy surgery cases, two cases of primary epileptogenicity expressed within the VP-PC were identified and are detailed to bring attention to this electroencephalographically-hidden area of ictal expression. Details of their investigation and surgical treatment illustrate distinctly different approaches addressing the problem and bringing about a seizure-free outcome.