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Prolonged Epileptic Disorders : Identification and Rescue Treatment Strategies - Full PDF Volume 16, special issue 1, October 2014

PREFACE
S1 - Understanding the mechanisms, identifying and treating prolonged epileptic seizures
Alexis Arzimanoglou, Lieven Lagae

EFFECTS OF ACUTE/PROLONGED SEIZURES IN HUMANS
S2 - Setting the scene: defi nition of prolonged seizures, acute repetitive seizures, and status epilepticus. Do we know why seizures stop?
Helen J. Cross

S6 - What are the effects of prolonged seizures in the brain?
Rod C. Scott

S12 - What is more harmful, seizures or epileptic EEG abnormalities? Is there any clinical data?
Gregory L. Holmes

FUNDAMENTAL RESEARCH DATA
S23 - Prolonged seizures: what are the mechanisms that predispose or cease to be protective? A review of animal data
Rüdiger Köhling

S37 - Outcome of status epilepticus. What do we learn from animal data?
Stéphane Auvin, Nina Dupuis

CLINICAL EXPERIENCE WITH BENZODIAZEPINES
S44 - Overview of clinical effi cacy and risk data of benzodiazepines for prolonged seizures
Lieven Lagae

S50 - What are the best ways to deliver benzodiazepines in children/patients with prolonged convulsive seizures?
Richard F.M. Chin

DEVELOPMENTAL PHARMACOLOGY OF BENZODIAZEPINES
S59 - Developmental pharmacology of benzodiazepines under normal and pathological conditions
Meaghan K. McGoldrick, Aristea S. Galanopoulou

S69 - Treating acute seizures with benzodiazepines: does seizure duration matter?
David E. Naylor

INDICATIONS IN CLINICAL PRACTICE
S84 - Are febrile seizures an indication for intermittent benzodiazepine treatment, and if so, in which cases?
Peter Camfield, Carol Camfield

S89 - Syndromes at risk of status epilepticus in children: genetic and pathophysiological issues
Bernd A. Neubauer, Andreas Hahn

S96 - Syndromes with very low risk of acute prolonged seizures
Thomas Bast

FUTURE TRIALS
S103 - Is there a need for further trials for the treatment of prolonged seizures?
John M. Pellock, Syndi Seinfeld