John Libbey Eurotext

Progressive Myoclonus Epilepsy: The Gene-Empowered Era Volume 18, supplement 2, September 2016


The progressive myoclonus epilepsies (PMEs) are “progressive”, because they worsen with time and are generally fatal. They are “myoclonus”, because these patients generally have frequent, often constant, myoclonus, which is commonly, though not invariably, cortical. They are “epilepsies”, because in addition to the myoclonus the patients suffer convulsive and other types of seizures, which are soon intractable, and which in many cases precipitate death in status epilepticus. But the PMEs are in most [...]