John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

Continuous spikes and waves during slow sleep in a child with karyotype 47, XYY Volume 16, issue 2, June 2014


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1 Regional Epilepsy Centre, Azienda Bianchi-Melacrino-Morelli Hospital, Reggio Calabria
2 Department of Medical and Surgical Sciences, Magna Græcia University, Catanzaro
3 Pediatric Unit, San Francesco di Paola Hospital, Paola (CS)
4 Pediatric Unit, Azienda Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy
* Correspondence: Umberto Aguglia Regional Epilepsy Centre, Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy
  • Key words: chromosomal disorder, CSWSS, centro-temporal spikes, seizure
  • DOI : 10.1684/epd.2014.0651
  • Page(s) : 223-6
  • Published in: 2014

The XYY syndrome is a sex chromosome aneuploidy occurring in one of 1,000 live male births. Only few data exist regarding the correlation between this syndrome and epilepsy. An EEG pattern suggestive of benign focal epilepsy with centro-temporal spikes has recently been described in four XYY patients. We report the first patient with XYY trisomy, rolandic spikes, and atypical evolution with continuous spikes and waves during slow sleep (CSWSS). The present report suggests that the association between an EEG pattern similar to that of BECTS and 47, XYY karyotype may not be coincidental. Moreover, we show that an atypical evolution with CSWSS may occur in this chromosomal disorder.