JLE

Epileptic Disorders

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Characteristic phasic evolution of convulsive seizure in PCDH19-related epilepsy Volume 18, issue 1, March 2016

Figure 1

Ictal EEG of Patient 1. (A) Initial 8-Hz rhythmic waves with Cz and C3 predominance (*1) were followed by 13-Hz rhythmic waves predominantly at Cz (*2), which then gradually changed to diffuse slow waves (*3). These rhythmic waves terminated as high-amplitude, diffuse, slow wave bursts with spikes over the bilateral frontal area. Motion artefacts due to postictal oral automatism were present on bilateral temporal traces (*4). (B) Ictal EEG of Patient 1 during the same series of clusters. The ictal rhythmic sequence was predominantly on the left side.

Figure 2

Ictal EEG of Patient 2. (A) EEG changes began with sharp transients at T5-O1 subclinically (*1). After irregular slow waves (probably representing motion artefacts), recruiting rhythms appeared predominantly at the left fronto-temporal region (*2) and then spread diffusely (*3); thereafter, these rhythms gradually changed to generalised spike and wave bursts. Motion artefacts due to postictal oral automatism were present on bilateral temporal traces. (B) Another seizure recorded one year later. Recruiting fast waves emerged predominantly over the right hemisphere and gradually changed to spike and wave bursts on the right side and slow wave bursts on the left side.