John Libbey Eurotext

European Journal of Dermatology

Successful use of etoposide for pyoderma gangrenosum associated with myelodysplastic syndrome and trisomy 8: cytokine profiles during treatment Volume 27, issue 5, September-October 2017


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1 Department of Dermatology
2 Department of Hematology,
Oncology and Respiratory Medicine: Okayama University Graduate School of Medicine,
and Pharmaceutical Sciences,
3 Department of Dermatology,
Okayama City Hospital,

Neutrophilic dermatoses, such as Sweet syndrome and pyoderma gangrenosum (PG), are often associated with inflammatory bowel diseases, Takayasu's arteritis, and haematological malignancies, such as myeloid leukaemia and myelodysplastic syndrome (MDS) [1]. We report a patient with steroid-resistant PG associated with trisomy 8 and MDS, focusing on the successful use of etoposide prior to haematopoietic stem cell transplantation.A 47-year-old woman presented with a sudden onset of an oedematous lesion [...]