John Libbey Eurotext

European Journal of Dermatology


Spindle cell haemangioendothelioma Volume 7, issue 2, March 1997


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Department of Dermatology, University of Siena, Policlinico “Le Scotte”, Viale Bracci, I-53100 Siena, Italy.
  • Key words: Kaposi’s sarcoma, spindle cell haemangioendothelioma, vascular tumors.
  • Page(s) : 137-8
  • Published in: 2000

Spindle cell haemangioendothelioma is an uncommon vascular lesion first described in 1986 by Weiss and Enzinger. It develops in the dermis and subcutis, at any age and in either sex, manifesting as multiple, painless, reddish, blue nodules, mainly on the distal extremities. The cardinal histological features, as described to date, are cavernous vascular spaces (often containing thrombi), mixed with a variably prominent solid component, consisting of bland spindle cells and plump epithelioid cells, often with cytoplasmic vacuoles. Here we report a case of spindle cell haemangioendothelioma. The main clinical and histopathological features of this rare neoplasm are reviewed, and the differential diagnoses with respect to other vascular tumors are discussed.