European Journal of Dermatology
MENUPigmentary mosaicism of the hypopigmented type (hypomelanosis of Ito): hypopigmented lesions with serrated and irregular borders Volume 24, issue 6, November-December 2014
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Department of Dermatology,
Kinki University Faculty of Medicine,
377-2 Ohno-Higashi,
Osaka-Sayama,
Osaka 589-8511, Japan
Kinki University Faculty of Medicine,
377-2 Ohno-Higashi,
Osaka-Sayama,
Osaka 589-8511, Japan
- DOI : 10.1684/ejd.2014.2424
- Page(s) : 690-1
- Published in: 2014
Hypomelanosis of Ito (HI) was first reported in 1952 [1]. In 1992, Ruiz-Maldonado et al. proposed diagnostic criteria for HI [2]. It is typically characterized by more than two hypopigmented segments with extracutaneous manifestations, i.e. nervous and/or musculoskeletal abnormalities [2]. Most patients have linear unilateral or bilateral lesions but patchy lesions may also occur [2]. Extracutaneous abnormalities include mental and motor retardation, seizures, microcephaly, hypotonia and sensorineural [...]