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European Journal of Dermatology

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Pembrolizumab-associated mucous membrane pemphigoid during complete remission of metastatic non-small cell lung cancer Volume 32, issue 6, November-December 2022

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Authors
1 Department of Dermatology and Venereology, Robert Debré Hospital, 51100 Reims, France
2 Jeanne de Navarre Hospital, 02400 Château-Thierry, France
3 Department of Pulmonary Medicine, Jeanne de Navarre Hospital, 02400 Château-Thierry France
4 Reims Champagne Ardenne University, IRMAIC, EA7509, 51100 Reims, France

Anti-programmed cell death protein-1 (PD-1) antibodies are immune checkpoints inhibitors (ICIs) used in the management of several types of malignancy that have considerably improved the prognosis of patients with advanced cancers [1]. However, these medications are associated with multiple immune-related adverse events (irAEs), of which 40% are cutaneous, consisting mainly of non-specific rashes, pruritus, and vitiligo [2]. Several cases of autoimmune bullous diseases (AIBD), mainly bullous pemphigoid [...]