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European Journal of Dermatology

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Mechanisms of UV-induced immunosuppression. Link between UV-induced tolerance and apoptosis Volume 8, issue 3, April-May 1998

Author
Department of Dermatology, University Münster, Münster, Germany.
  • Page(s) : 196-7
  • Published in: 1998

Exposure to UV light impairs sensitization to haptens applied directly to the irrradiated skin area [1, 2]. In addition, hapten-specific tolerance develops, which is due to the generation of hapten-specific T suppressor cells [3]. Although the transfer of tolerance by injecting T cells from UV-exposed mice into naive recipients was described more than 10 years ago, the mechanisms by which T suppressor cells mediate tolerance still [...]