John Libbey Eurotext

European Journal of Dermatology

Juvenile dermatomyositis positive for anti-DNA mismatch repair enzyme antibodies Volume 27, issue 1, January-February 2017

Figures

  • Figure 1
Authors
1 Department of Dermatology,
Kashiwa Hospital,
The Jikei University School of Medicine,
Chiba,
2 Department of Dermatology,
The Jikei University School of Medicine,
Tokyo,
3 Department of Pediatrics,
Kashiwa Hospital,
The Jikei University School of Medicine,
Chiba,
4 Department of Dermatology,
Nagoya University Graduate School of Medicine,
Nagoya,
Japan

Myositis-specific autoantibodies, such as anti-transcription intermediary factor (TIF) 1-γ and anti-aminoacyl transfer RNA synthetase antibodies, are exclusive to idiopathic inflammatory myopathies (IIMs). Recently, autoantibodies to DNA mismatch repair enzymes (MMREs) were identified in IIMs [1-3], but little is known about the significance of these antibodies in IIMs. Here, we present the first case of juvenile dermatomyositis (JDM) with autoantibodies mono-specific to MMREs.An 11-year-old Japanese [...]