JLE

European Journal of Dermatology

MENU

Incidental cases of subacute cutaneous lupus erythematosus in association with malignancy Volume 18, issue 6, Novembre-Décembre 2008

Figures

See all figures

Authors
Clinic of Dermatology, Venereology und Allergology, University of Leipzig Ph.-Rosenthalstr. 23-25, 04103 Leipzig, Germany, Clinic of Dermatology, University Hospital of Erlangen, Erlangen, Germany

Malignancy and chronic inflammatory diseases seem to be associated to one another. Here we review the literature regarding subacute cutaneous lupus erythematosus (SCLE) and concomitant neoplasia on the basis of 3 short case reports of patients with SCLE who developed breast cancer and lung cancer respectively after long-term disease activity and immunosuppressive therapy. Possible hypotheses for this co-incidence could be: i) malignancy as a consequence of chronic inflammation, ii) malignancy as a consequence of immunosuppressive therapy, iii) paraneoplastic disease, iv) local malignancy following a persisting proliferative or reparative process or v) only coincidental occurrence.