GVHD-like erythroderma in the clinical course of thymoma-associated myasthenia gravis

Hisashi Nomura; Shigeaki Suzuki; Fumiyo Yasuda-Sekiguchi; Masayuki Amagai; Satoshi Yamada; Jin Nakahara; Norihiro Suzuki; Mitsutomo Kohno; Takeru Funakoshi

doi:10.1684/ejd.2017.2993

European Journal of Dermatology

GVHD-like erythroderma in the clinical course of thymoma-associated myasthenia gravis Volume 27, issue 3, May-June 2017

Figures

Figure 1

A 42-year-old Japanese woman with invasive thymoma suffering both graft-versus-host disease (GVHD)-like erythroderma and myasthenia gravis. A) Chest X-ray and computed tomography showed invasive thymoma. B) GVHD-like erythroderma on the patient's face, trunk and extremities. C) A skin biopsy showed parakeratosis in the epidermal layer, with lymphocytic infiltration (hematoxylin and eosin staining with low and high magnification).

Figure 1

Tables

Table 1

Authors

Hisashi Nomura ¹

Shigeaki Suzuki ²

Fumiyo Yasuda-Sekiguchi ¹

1 Department of Dermatology,
Keio University School of Medicine,
Tokyo,
Japan

2 Department of Neurology,
Keio University School of Medicine,
Tokyo,
Japan

3 Division of General Thoracic Surgery,
Department of Surgery,
Tokai University School of Medicine,
Isehara,
Japan

DOI : 10.1684/ejd.2017.2993
Page(s) : 314-5
Published in: 2017

Graft-versus-host disease (GVHD) occasionally occurs during transplantation or transfusion. It is rarely associated with thymoma and can present as a symptom of thymoma-associated multi-organ autoimmunity [1]. It has unfavourable prognosis due to complications, such as colitis or liver dysfunction [1-3]. Although, thymoma is a benign tumour that is radically resectable at an early stage, it is sometimes accompanied by autoimmune disorders and requires long-term management. Myasthenia gravis (MG) [...]

European Journal of Dermatology

GVHD-like erythroderma in the clinical course of thymoma-associated myasthenia gravis Volume 27, issue 3, May-June 2017

Figures

Figure 1

Tables