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European Journal of Dermatology

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Generalized morphea with preceding severe pain and coexistent early primary biliary cirrhosis Volume 25, issue 4, July-August 2015

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  • Figure 1
Authors
1 Department of Dermatology,
2 Department of Gastroenterology and Hepatology,
Kyoto University Graduate School of Medicine,
54 Shogoin-Kawara, Sakyo-ku, Kyoto, Japan

Localized scleroderma is a chronic sclerodermic disease that involves the skin and subcutaneous tissues without internal organ manifestations. Generalized morphea (GM) is a form of localized scleroderma, which is characterized by widespread skin involvement with multiple sclerotic plaques and hyperpigmentation [1]. Patients with GM classically present with localized sclerotic skin lesions without any associated symptoms including pain.Primary biliary cirrhosis (PBC) is a chronic cholestatic liver [...]