JLE

European Journal of Dermatology

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Generalized granuloma annulare and hepatitis B vaccination Volume 8, issue 6, September 1998

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Authors
Dermatology department, Hôpital de l’Antiquaille, rue de l’Antiquaille, 69321 Lyon Cedex 05, France.

As hepatitis B vaccination is becoming generalized in Europe, cutaneous adverse events are being more frequently reported in the literature. We report the first case of generalized granuloma annulare following hepatitis B immunization. A 51-year-old woman presented a generalized granuloma annulare one month after the one-year booster injection of the hepatitis B vaccine. The lesions resolved with sulfone therapy. We observed an identical recurrence three weeks after the five-year booster.