John Libbey Eurotext

European Journal of Dermatology


Efficacy of biologics in psoriasis patients under hemodialysis Volume 27, issue 5, September-October 2017


  • Figure 1
1 CHU Nancy, France
2 CHU Montpellier, France
3 APHP, Paris, France
4 APHM, Marseille, France
5 CHU Besançon, France

The biologics anti-tumour necrosis factor (TNF)-α, anti-interleukin (IL)-12, and IL-23 are indicated for severe-to-moderate plaque psoriasis in patients who fail to respond, or have contraindication, to systemic treatments or phototherapy. Chronic kidney disease (CKD) is a contraindication for many treatments. There are limited data about the use of biologics in CKD. No contraindication nor renal toxicity are reported, and the pharmacokinetic and impact of dialysis on their efficacy are unknown. [...]