European Journal of Dermatology
MENUDapsone efficacy and adverse events in the management of mucous membrane pemphigoid Volume 20, issue 2, March-April 2010
Authors
Oral Medicine Unit UCL, Eastman Dental Institute and UCLHT Eastman Dental Hospital, 256 Gray’s Inn Road, London WC1X 8LD
- DOI : 10.1684/ejd.2010.0847
- Page(s) : 223-4
- Published in: 2010
Auteur(s) : Anne M Hegarty, Martyn Ormond, Maureen Sweeney, Tim Hodgson Oral Medicine Unit UCL, Eastman Dental Institute and UCLHT Eastman Dental Hospital, 256 Gray’s Inn Road, London WC1X 8LD Dapsone is a synthetic sulfone with antimicrobial and anti-inflammatory properties. It inhibits migration and adherence of neutrophils and synthesis of prostaglandins E2 [1, 2]. By blocking neutrophil migration, dapsone may act to prevent inflammation and new vesicle formation in mucous membrane pemphigoid [...]