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European Journal of Dermatology

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Cardiovascular risk factors and cardiovascular diseases in patients with moderate to severe psoriasis under systemic treatment. PSO-RISK, descriptive study Volume 24, issue 6, November-December 2014

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Authors
1 Dpt Dermatology, Hospital 12 de Octubre, Av de Córdoba, s/n, 28041 Madrid, Spain
2 Dpt Dermatology, Hospital General Universitario, Alicante, Spain
3 Dpt of Dermatology, Hospital General Universitario, Valencia, Spain
4 Dpt of Dermatology, Hospital Germans Trias i Pujol, Badalona, Spain
5 Medical Affairs, Merck Sharp & Dohme of Spain, Josefa Valcárcel 38, 28027 Madrid, Spain
6 Dpt of Dermatology, Hospital de la St Creu i S Pau, Barcelona, Spain
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Background: The prevalence of cardiovascular risk factors (CVRF) in psoriasis has not been studied in large Spanish samples. Objective: To assess the prevalence of major CVRFs in psoriasis patients requiring systemic treatments. Material and Methods: Cross-sectional study in psoriasis patients from 33 hospital dermatology offices throughout Spain. Blood pressure (BP) was measured and a fasting lab test was performed. Each CVRF was diagnosed according to the recommendations of international societies. Results: In 368 patients (mean age 48 years old, 36% women), 80.2% had at least one CVRF. The prevalence of each CVRF was similar in men and women and slightly higher in patients with psoriatic arthritis and in patients with a history of more severe disease. The percentage of patients treated with drugs to control CVRF was low (∼50% of those with each CVRF). A total of 20.7% had experienced some cardiovascular disease (CVD) episode. Conclusion: The prevalence of CVRF was high, higher than in the general Spanish population, and 20% had already suffered CVD. However, the percentage with drug treatments for CVRF was low.