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European Journal of Dermatology

Carcinoma of the penis arising in differentiated epithelial dysplasia associated with lichen sclerosus Volume 7, issue 2, March 1997

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We report 2 cases of carcinoma of the penis occurring on thick white lesions (leukoplakia) associated with genital lichen sclerosus. The histological features of the whitish plaques are similar to the so-called, differentiated, intra-epithelial neoplasia defined by the International Society for the Study of Vulvar Disease (ISSVD), and should be considered as precancerous lesions.