John Libbey Eurotext

European Journal of Dermatology


Acute generalized exanthematous pustulosis induced by mianserin Volume 28, issue 4, July-August 2018


  • Figure 1
Department of Clinical Pharmacology Centre Hospitalier Universitaire, Poitiers, France

Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous reaction [1], characterized by extensive, non-follicular, sterile pustules on an erythematous background, associated with fever. Up to 90% cases are induced by drugs, most commonly antibiotics and terbinafine. We present the first case of AGEP associated with the antidepressant, mianserin.A 46-year-old man, with no personal history of psoriasis, was admitted complaining of a generalized pruritic pustular eruption. Seven [...]