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European Journal of Dermatology

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Acral lentiginosis associated with tegafur/gimeracil/oteracil (TS-1) Volume 27, issue 2, March-April 2017

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Authors
Department of Dermatology, Ajou University School of Medicine, 164 World Cup-ro, Yeongtong-gu, Suwon 443-380, South Korea

Acral lentiginosis refers to an outbreak of multiple lentigines confined to acral sites, e.g. hands and feet. It is known to be associated with immunodeficiency conditions, such as acquired immunodeficiency syndrome (AIDS) or immunosuppressive treatments [1-3]. Some authors consider the condition as a paraneoplastic syndrome [1].Tegafur/gimeracil/oteracil (TS-1) is a combined oral chemotherapeutic agent containing 20 mg of tegafur, a prodrug converted by cells to fluorouracil (FU) and other components [...]