Misr International University, Faculty of Pharmacy, Department of Biochemistry, Cairo, Egypt
Cairo General Hospital, Chemistry Department, Cairo, Egypt
Correspondence: M. Schaalan. Misr International University, Faculty of Pharmacy, Department of Biochemistry, Km 28, Cairo-Ismailia Road, P.O. Box 1, Heliopolis, Cairo, Egypt
Both authors contributed equally.
- Key words: osteoprotegerin, KIM-1, cystatin C, sepsis, acute kidney injury
- DOI : 10.1684/ecn.2017.0393
- Page(s) : 52-62
- Published in: 2017
Though significant progress has been made towards new diagnostic approaches for early detection of acute kidney injury (AKI) induced by different factors, there is still an urgent demand for a more specific and predictive biomarker for each type. The aim of this study is to unravel the potential diagnostic utility of circulating osteoprotegerin (OPG) in septic patients who developed AKI in the ICU, compared to cystatin C (a renal function maker) and KIM-1 (a kidney damage marker).