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Extracellular Mg concentration and Ca blockers modulate the initial steps of the response of Th2 lymphocytes in co-culture with macrophages and dendritic cells Volume 26, issue 1, January-February-March 2015

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Authors
1 Department of Immunology, Pathophysiology and Veterinary Preventive Medicine, Wroclaw University of Environmental and Life Science, C.K. Norwida 31, 50-375 Wroclaw, Poland

Recognition of a pathogen is a fundamental function of the immune system. Important players in this process are the so-called antigen-presenting cells (APCs) which engulf, process, and then present antigens to T lymphocytes. APCs also produce the signals necessary for the activation of lymphocytes into effector cells that actively carry out immune defenses. In addition, they prime self-reactive T cells [1]. APCs are a heterogeneous population that includes Langerhans cells, macrophages, dendritic [...]