European Cytokine Network
MENUChemokine and chemokine receptor patterns in patients with benign and malignant salivary gland tumors: a distinct role for CCR7 Volume 28, issue 1, March 2017
Authors
Background
1 Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Pathology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
3 Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran
4 Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
* Correspondence: A ghaderi, Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
M Razmkhah, Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
- Key words: salivary gland tumors (SGTs), chemokine, chemokine receptor
- DOI : 10.1684/ecn.2017.0388
- Page(s) : 27-35
- Published in: 2017
To explore the molecular mechanisms involved in pathophysiology of malignant and benign salivary gland tumors (SGTs), we investigated main tumor-inducing chemokines and chemokine receptors, CXCL12/CXCR4/ACKR3 (CXCR7), CXCR3/CXCL10, CCR5/CCL5, CCL21/CCR7, CCL2, CCR4, CXCR5, CCR6, and CXCL8 in tumor tissues.