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Chemokine and chemokine receptor patterns in patients with benign and malignant salivary gland tumors: a distinct role for CCR7 Volume 28, issue 1, March 2017

Figures


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  • Figure 4

Tables

Authors
1 Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Pathology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
3 Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran
4 Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
* Correspondence: A ghaderi, Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran M Razmkhah, Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Background

To explore the molecular mechanisms involved in pathophysiology of malignant and benign salivary gland tumors (SGTs), we investigated main tumor-inducing chemokines and chemokine receptors, CXCL12/CXCR4/ACKR3 (CXCR7), CXCR3/CXCL10, CCR5/CCL5, CCL21/CCR7, CCL2, CCR4, CXCR5, CCR6, and CXCL8 in tumor tissues.