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Virus and semen: implication in assisted medical procreation


Virologie. Volume 6, Number 2, 105-11, Mars - Avril 2002, Revues

Résumé   Article gratuit  

Author(s) : C. Pasquier, L. Bujan, J. Puel, J. Izopet

Summary : Many viruses are sexually transmitted and can be found in male or female genital secretions. This is the case of HBV, HPV, HSV, CMV, HHV8, HTLV and HIV. Since HIV1 leads to severe chronic infection serodiscordant couples cannot conceive without risk of partner contamination. They ask for assisted medical procreation (AMP) techniques to reduce as low as possible this risk. HCV can be detected in semen but does not seem to be easily sexually transmitted, then only infertile HCV serodiscordant couples ask for AMP. Spermatozoa processing reduces HIV1 level and HCV under detection levels of sensitive PCR techniques. Since gametes are laboratory processed, they have to be legally controlled for virus that may contaminate receiving patients. Like in blood transfusion or organ/tissue transplantation, viral security is a key issue in AMP.

Keywords : Spermatozoa - Reproduction - Sexual transmission - HIV - HCV.

 

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