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 Printable version |
Analysis of the effect of perioperative magnesium sulphate on minimal alveolar concentration of desflurane using bispectral index monitoring |
Magnesium Research. Volume 24, Number 4, 181-8, December 2011, Original article
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Author(s) : Yakup Tomak, Murat Tekin, Ismail Kati, Ceyda Belenli, Meltem Aydogmus |
Summary : <\;p>In this study we aimed to analyze the effect of perioperative magnesium sulphate (MgSO
4) on minimal alveolar concentration (MAC) of desflurane using bispectral index (BIS) monitoring.<\;/p><\;p>Sixty patients undergoing abdominal surgery under general anesthesia were randomized into two groups: Mg – receiving perioperative MgSO
4 supplementation and C – control. Anesthesia was titrated to maintain the BIS value between 45-55.<\;/p><\;p>MAC values, tachycardia and hypertension during intubation was found to be lower in group Mg compared to group C (p<\;0.001). Time to extubation, verbal cooperation and eye opening was longer in patients receiving infusion of MgSO
4 (p<\;0.001).<\;/p><\;p>We concluded that perioperative MgSO
4 infusion may be used as an adjunct as it decreases MAC of desflurane and suppresses the hemodynamic response to intubation.<\;/p> |
Keywords : magnesium, desflurane, minimal alveolar consantration, bispectral index |
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