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Editorial |
Magnesium Research. Volume 19, Number 2, 89-90, June 2006, Editorial
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Author(s) : Jean Durlach . |
ARTICLE
Auteur(s) : Jean Durlach
This second issue of volume 19 of Magnesium Research 2006 testifies
to the vitality of research on magnesium.It includes original
experimental, clinical and review papers which originate from many
parts of the world and two In Memoriam articles concerning two
great magnesium researchers, R. Fehlinger and H. Morii,
who sadly passed away.1. One original experimental paper is
presentedVan Orden et al. (Provo, Utah, USA) showed that blood
leukocytes in young magnesium deficient adult rats increased in a
threshold manner. Rats fed diets with 60, 120 or 208 ppm Mg for
four weeks did not have an increase in blood leukocytes counts in
comparison with controls fed a diet of 850 ppm. However, in rats
fed 30 ppm Mg, there was a significant increase in total blood
leukocytes counts. Lymphocytes were particularly increased: among
them, the percentage of B cells decreased, but as total counts
in blood, B cells, CD4 cells and CD 8 cells were significantly
increased.2. Next come three original clinical papersG. Grases
et al. (Palma of Mallorca, Spain) evaluated stress and anxiety in
University science students. The students suffered a significant
increase in anxiety as a consequence of exams. It seems related to
a urinary magnesium increase without any urinary calcium
increase.K. Pasternak et al. (Lublin, Poland) analyzed the changes
in blood magnesium levels in patients undergoing coronary artery
bypass grafts (CABG) with extracorporeal circulation. The blood
concentration of magnesium decreased during extracorporeal
circulation and immediately after surgery. It increased in the
morning of the first and second post-operative days.In another
study, K. Pasternak et al. (Lublin, Poland) examined the effects of
pre-operative magnesium supplementation on blood catecholamines.
CABG induces a decrease of magnesium and an increase in epinephrine
and in norepinephrine. Oral preoperative magnesium supplementation
reduces magnesium and catecholamines disorders caused by
CABG.3. Next comes one original review paperB.P. Meloni et al.
(Nedlands, Australia) highlighted the discrepancy between
neuroprotective activity associated with animal models of cerebral
ischemia and clinical stroke trials (IMAGE trial, particularly)
which found magnesium to be largely ineffective. It is possible
that magnesium is only neuroprotective when combined with
post-ischaemic hypothermia. Future preclinical and clinical
cerebral ischaemia trials with magnesium should consider combining
treatment with mild hypothermia.[[Please provide a title for this
section or delete the number]] 4. Abstracts of the last issue of
the Journal of Japanese Society for Magnesium Research, two In
memoriam concerning respectively R. Fehlinger and H. Morii, the
Calendar of Magnesium Meetings followed by the Forthcoming Contents
complete this second 2006 issue of our quarterly international
journal Magnesium Research.
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