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Editorial


Magnesium Research. Volume 18, Number 1, 5-6, March 2005, Editorial



Author(s) : Jean Durlach .

ARTICLE

Auteur(s) :, Jean Durlach

This first issue of 2005 testifies to the vitality of research on magnesium originating from many parts of the world.It includes experimental and clinical studies in biology, cardiology, dietetics, epidemiology, hematology, internal medicine, neonatalogy, physiology and therapeutics.1. One original experimental paper is presented.F. Corica et al. (Messina, Cosenza, Italy) demonstrated that leptin-dependent platelet aggregation is inhibited ex vivo by MgSO4 in a dose-dependent manner. The blocking of the hydrolysis of phosphoinositide and of intracellular Ca mobilisation may be involved in these findings.2. Next come two original clinical papers.C.Y. Yang et al. (Kaohsiung, Taiwan) investigated the possible association between the risk of death from sudden infant death syndrome (SIDS) and the levels of magnesium in drinking water from municipal supplies in a matched case-control study. There is a significant trend toward a decreased risk of SIDS with increasing magnesium levels in drinking water.J. Durlach et al. (Paris, France) stressed the importance of the chronopathological forms of asthma through magnesium depletion with hypofunction or hyperfunction of the biological clock. The treatment of these clinical forms of asthma involves the maintenance of a standard dosing schedule of anti-asthma drugs, a balanced Mg intake and the appropriate treatment of the chronopathological disorders: mainly diverse forms of “darkness therapy” in hypofunction of the biological clock and of “phototherapy” in hyperfunction.3. A review paper follows.W. Bobkowski et al. (Poznan, Poland; Paris, France) attempted to evaluate the importance of magnesium status in the pathophysiology of idiopathic mitral valve prolapse (IMVP). IMVP appears to be a frequent complication of the neural form of magnesium deficit. If it is necessary to obtain a balanced magnesium status, the early introduction of nutritional magnesium supplementation, preferably in childhood, may protect from the onset of symptoms of magnesium deficit, particularly from IMVP.4. The selected Abstracts of the last issues of the Journal of Elementology and of the 25th Magnesium Symposium of the German Magnesium Research Society (Munich, 8-9 October 2004), two “In memorian” concerning the loss of two eminent magnesium researchers: Pierre Larvor and Mildred Seelig, the Calendar of Magnesium Meetings followed by the Forthcoming Contents complete the first 2005 issue of our quarterly international journal Magnesium Research.


 

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