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 Printable version |
The influence of α‐zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny |
Magnesium Research. Volume 16, Number 2, 106-10, June 2003, ORIGINAL ARTICLE
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 Free Article
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Author(s) : Kazimierz Pasternak, Małgorzata Kiełczykowska, Małgorzata Sztanke, Andrzej Borzecki |
Summary : The purpose of the research work was to study the influence of α‐zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received α‐zearalenol at the doses of: 0.05, 0.5 or 1 mg·kg
‐‐1 b.w. After delivery, brain, liver and kidneys of female rats and their progeny were removed and magnesium concentration was measured in cellular subfractions of these tissues. α‐zearalenol reduced Mg‐level in all the cellular subfractions of female rat tissues. In progeny tissues, α‐zearalenol decreased magnesium concentration in nuclear subfraction only. In mitochondrial and cytosol subfractions it increased Mg‐concentration. The changes in magnesium concentration were depended on α‐zearalenol doses and tissue nature. The magnesium concentration decrease was higher in female rats than in progeny tissues. |
Keywords : α‐zearalenol, magnesium, pregnant rats, progeny. |
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