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Modulation of the allergen-induced human IgE response in Hu-SCID mice: inhibitory effect of human recombinant IFN-gamma and allergen-derived lipopeptide Volume 12, numéro 3, September 2001

Auteurs
INSERM U. 416 Institut Pasteur de Lille, 1, rue du Pr Calmette, BP 245, 59019 Lille Cedex, France.
  • Page(s) : 453-61
  • Année de parution : 2001

INTRODUCTION Many studies have been devoted to understanding the mechanisms of the human allergic reaction, which is mainly characterized by an enhanced IgE production and a local inflammatory reaction. The IgE response is dependent on several factors including genetic background and conditions of exposure (dose of allergens, timing and route of allergen introduction) [1, 2]. The IgE production is also directly dependent on the nature of [...]