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European Cytokine Network

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Monocyte chemotactic protein-3 Volume 12, numéro 4, December 2001

Auteurs
Laboratory of Molecular Immunology, Rega Institute for Medical Research, Minderbroedersstraat 10, B-3000 Leuven, Belgium
  • Page(s) : 554-60
  • Année de parution : 2002

INTRODUCTION Chemokines constitute a rapidly growing family of low molecular weight proteins, characterized by the conservation of four cysteines, which are important for their tertiary structure [1]. Disulfide bridges are formed between cysteines one and three and between cysteines two and four. Chemokines have been classified into two major subfamilies, namely CXC and CC chemokines, depending on whether their first two NH2-terminal cysteines [...]